

Sena is like any other shy kid starting high school; he's just trying to survive. Constantly bullied, he's accustomed to running away. Surviving high school is about to become a lot more difficult after Hiruma, captain of the school's American football team, witnesses Sena's incredible agility and speed during an escape from some bullies. Hiruma schemes to make Sena the running back of his school team, The Devil Bats, hoping that it will turn around the squad's fortunes from being the laughingstock of Japan's high school leagues, to title contender. To protect his precious star player from rivaling recruiters, he enlists Sena as "team secretary," giving him a visored helmet and the nickname "Eyeshield 21" to hide his identity. The Devilbats will look to make their way to the Christmas Bowl, an annual tournament attended by the best football teams in Japan, with "Eyeshield 21" leading the way. Will they be able to win the Christmas Bowl? Will Sena be able to transform from a timid, undersized freshman to an all-star player? Put on your pads and helmet to find out!








It is Sena's first day of High School. And from now on his school life will be different. Sena has vowed not to be made a gopher like he has been in the past. But its bad luck for Sena after the Football Team Captain, Hiruma catches Sena running away from the Hah Brothers. Will Sena join the team and help the football team make it to the Christmas Bowl?
Sena may be on the Deimon Devilbats football team, but he realizes that he doesn't know anything about the game of Football. Can Sena learn how to play, or will he give up before the Spring season?
Its Sena's first game as EyeShield 21, and he doesn't know what to do. As the Deimon Devilbats lose, Sena also has to make Mamori believe he isn't EyeShield 21, or he won't be able to play for the Deimon Devilbats ever again. Can Sena get the winning touchdown and keep Mamori beliving he's the team manager and not EyeShield 21?
Sena decides that he needs to get away from having Mamori babying him all the time, so he decides to train alongside the football team, much to her objections.
The power of the Ojo White Knights almost overwhelms Sena, but a little pep talk from Kurita boosts his spirits and he begins to run with a new confidence in his teammates.
After watching Deimon score so easily with Eyeshield-21's speed, Ojo's coach sends in Shin to put an end to Eyeshield 21.
With Shin on the field, Oujo retakes the lead and sets the tone for the game. Sena, having suffered the brunt of Shin's tackles, begins to have second thoughts about playing.
Despite Ojo's overwhelming lead, the Devil Bats keep going. Unfortunately, for Ojo, Sakuraba strays onto the field and gets knocked down by EyeShield. Sena scores a small victory for himself, having managed to finally out-run Shin.
While searching for new players, including a Reciever, Sena finds a player named Raimon Tarou, who has great catching skills. But he is too late because Raimon is already trying out for the baseball team.
Sena, feeling very guilty about Sakuraba's injury, goes to see him in the hospital with Monta. Seeing how despondent Sakuraba is, Sena challenges him to be the hero he truly is.