JoJo's Bizarre Adventure (2000)

Seventeen-year-old Jotaro Kujo refuses to leave his jail cell, believing that he is possessed by an evil spirit. When Jotaro's mother, Holly, his grandfather Joseph Joestar, and the mysterious Mohammed Avdol come to try to coax him out, a battle erupts between Avdol's "evil spirit" Magician's Red and Jotaro's Star Platinum, revealed to be psychic manifestations known as Stands. (Source: Wikipedia)

Jotaro learns the secret of his Stand power and about his family's enemy, the vampire DIO. Later, Jotaro is attacked by Noriaki Kakyoin and his Stand Hierophant Green, an assassin controlled by DIO. When Holly falls into a Stand-induced coma, Joseph, Jotaro, and the others embark on a dangerous journey to Egypt to save her life and end the 100-year battle between DIO and the Joestar family.

When the private jet carrying Jotaro and his companions to Egypt suddenly bursts into flames, the plane is forced to land in the ocean. As the party drifts in a lifeboat, a large freighter pulls alongside and they climb aboard. To their shock, there is no crew to be found—and the only passengers left aboard are an orangutan and enemy Stand user Jean-Pierre Polnareff, user of Silver Chariot. However, Polnareff is another one of DIO's unwilling victims, and soon joins the group as they face off against the orangutan Forever and his Stand Strength.

At a stopover on the way to Egypt, Polnareff is attacked by the Stand known as the Hanged Man, an enemy Stand who has two right hands and can only be seen in reflections. Realizing that it must be controlled by the same Stand user that had killed his younger sister, Polnareff breaks away from the rest of the group to seek his revenge. Polnareff is lured into a trap set by J. Geil, user of the Hanged Man and his partner, Hol Horse. When some of the party come to his aid, Avdol is killed by Hol Horse's Stand the Emperor.

Kakyoin and Polnareff desperately seek a way to defeat the Hanged Man, who can strike out at them from within reflections while remaining invulnerable to their attacks. They must figure out a way to fight a Stand that can move at nearly the speed of light and can attack from anywhere.

A thick fog envelopes the group as they travel towards Egypt, so they seek refuge in a nearby town. There, the companions stumble across a strangely mutilated dead body lying on a street corner. An old woman arrives on the scene with the police, and offers to let them stay at her hotel for the night. In the hotel bar, Polnareff encounters Enya, a beautiful and mysterious young woman on a deadly quest of revenge of her own as Polnareff has killed her son J. Geil.