Nawaki (縄樹) was the younger brother of Tsunade and the grandson of the First Hokage. He was very much like Naruto Uzumaki in both appearance and personality and like Naruto, Nawaki also had the dream of becoming Hokage one day. He shared this dream with his sister on his twelfth birthday, who gave him their grandfather's necklace in the hopes that it would help him achieve is dream. The day after his birthday, Nawaki died in battle. His body was so heavily mutilated that it was beyond recognition. Orochimaru would later offer Tsunade to bring Nawaki back to life, together with Tsunade's lover Dan, in exchange for healing his arms. The resurrection would require a human sacrifice, though. She ultimately refuses, realizing that Nawaki and Dan would not want her to sacrifice the lives of others in exchange for theirs. (Source: Narutopedia)
Kaiza (カイザ) was a traveling fisherman, who came to the Land of Waves to seek opportunities. When he saved Inari from drowning, he took up the young boy to teach him about life and protect the things that were precious to him. He married Tsunami (Inari's mother) and acted as the role model for Inari. When Gat� tried to take over the Land of Waves, Kaiza tried to stop his business. Gat� used him as an example to people who had hoped to stand against him, by having his goons cut off his arms and killing him. (Source: Narutopedia)
The Second Hokage is the younger brother to the First Hokage and Tsunade's great-uncle. As the brother of the First, the Second Hokage was a member of the Senju Clan of the forest. The First and Second together fostered Konohagakure into a growing village. He was once the teacher of the Third Hokage. He was hailed for being the greatest master of water jutsu, being able to create water from nothing, allowing him to use any Suiton jutsu without requiring a source. He is later revived from the dead by Orochimaru using Impure World Resurrection to fight the Third Hokage during the Destruction of Konoha arc. His soul is eventually sealed into the stomach of the Death God, along with his brother and Orochimaru's arms. Along with his brother and Madara Uchiha, he was also one of the founders of the Hidden Leaf.
Mikoto Uchiha was the mother of Sasuke and Itachi. She was also Fugaku's wife. While she was alive, she seemed to like Sasuke better where her husband seemed to prefer Itachi. She was a very good mother, seeing as how Sasuke was able to talk to her better than his father. At one point, in order to cheer Sasuke up, she says that when she and Fugaku are alone Sasuke is all he talks about. Although she was Itachi's mother, she did have some suspicion about Itachi and knew that something was up. She was found dead with her husband during the Uchiha Clan Massacre, killed by Itachi.
Under the guidance of the Second Hokage, Tobirama Senju, Koharu and her teammates, Hiruzen and Homura, completed numerous missions and became close friends. When Hiruzen became the Third Hokage, Homura and Koharu became his councilors. With their years of experience and knowledge and their unending effort to make Konohagakure a better place, they eventually gained similar respect and social status as the Hokage himself. She holds the belief that the group is more important than any of its individual members. Because of this, she always tries to do what she thinks is the best for Konoha, even if it goes against the Hokage's or her opinion. She is also quite demure, but does not let this stop her from voicing her opinion. In fact, despite this, she is one of the few people able to put the Fifth Hokage in her place when she oversteps her authority. Like Homura, she is more militant than the Hokage she served under have been, and sometimes leans more to Danzo's point of view.
Name: Yugao Uzuki Gender: Female Age: Part I: 22, Part II: 25 Birthday: November 3 Height: 169,2 cm (5.551 ft) Weight: 50,5 kg (111.333 lb) Blood Type: A Affiliation: Konohagakure Occupation: ANBU She was Hayate Gekkou's lover and swore to avenge his death by Sunagakure.