Y�ko is the female lead of the series. She has two main abilities. The first is jaen where she shoots a coiling strand of fire out of her fingertips. There is also dai-jaen which is just a larger, more powerful variation. The second ability is shukichi, an ability which allows her to teleport objects. Strangely enough, although she is generally fearless in the face of evil spirits, she is terrified of normal dogs. During an escape from Hake, she met the child Keita, who was with her for three days and shared his chocolate cake with her, which became one of her favorite things. Due to this incident, she wanted to become Keita's inukami to make a contract with him. Yoko has feelings for Keita and she gets angry whenever he flirts with other girls.
Keita is the male lead of the show. He was considered a failure by his family due to his attitude towards their ancient duty to vanquish evil, treating it like a parttime job, and his initial inability to find an Inukami to bond with. Even though Yôko becomes his inukami and is fully interested in him, he has a bad habit of flirting with other girls; it is later revealed that Keita is mortified by the thought that, if he should develop a relationship with Yôko, he might become the father of a litter of puppies, rather than of a human baby. He is frequently punished for his transgressions by Yôko, to whom he had to promise that he would be loyal to her, that he would be hers and that he would be her toy, to do with whatever she wanted, before she would contract with him. He wears a dog's collar as a symbol of this pact - an item he originally intended as his 'vow gift' to Yôko. Yôko has frequently landed him in jail by teleporting him into a public place without his clothes, causing him to be mistaken for a streaker and arrested for indecent exposure. Due to this, he has been named Ra-ou (Naked King) by the city's perverts (male and female alike). Keita possesses considerable athletic skills, can make frog-shaped talismans up to around the size of his fist from rubber which he can use to make ranged attacks and is a practitioner of xingyiquan. However, a shinigami named 'Sea of Violence' commented his martial arts skill lack style. Despite his many flaws, Keita has considerable redeeming qualities; he is determined, usually fearless and loyal to his friends and to people under his protection.
Natsuki Mogi (茂木 なつき Mogi Natsuki) / Natalie Mogi - Takumi's love interest. Before she hooked up with Takumi, she engaged in enjo kosai to make some extra money. In the movie, it appears that she was engaged in prostitution or sugar-daddy kind of relationship with a middle aged man driving a white Mercedes. (Source: Wikipedia)
Second Lieutenant Maria Ross is put in charge of taking care of the Elric brothers during their stay in Central. She and her partner Brosh were assigned the task of guarding the Elrics due to Scar's return in Central and his previous attempt on Ed and Al's lives. Almost immediately, she takes on the role of a parental figure. She tries to give guidance to the brothers whenever she can. She took a liking to Ed and Al, and risked her life to calm Ed down when he was absorbing the red stone material inside laboratory 5. Both she and her partner Denny Brosh work under Major Alex Louis Armstrong. Source: Wikipedia
Anita is Romeo's childhood friend who had a deep crush on him. She lives in Sonogno Village. Anita wanted to marry Romeo in the future. When she learned that Romeo could possibly die while working as a chimney sweep in Milan, she tried to convince him not to leave Sonogno. Unfortunately, Romeo had already decided that he would go to Milan for the sake of his father, Roberto. Because of this, Anita became angry and very sad.