Domyouji Tsukasa is the leader of the F4. At the beginning of the series, he is Makino's biggest enemy, but as the story progresses, he becomes her love interest. Tsukasa is the heir to Domyoji Enterprises, and his family is extremely rich. They own various houses around the world, including an actual island, a house in Canada, and a house in New York City where his parents stay. Domyouji grew up somewhat lonely, as his parents were always overseas, and his sister—as loving as she could be—was either busy studying or, later in life, married and moved to Los Angeles. Also, his mother, Kaede, is cold to him, and although she loves him, wants to control his life. Tsukasa sometimes calls her "the old hag" and "witch". Before he met Makino, he was violent and ill-tempered, but after he became loyal and nice. As Tsukasa first started off being hard and tough to get though to; the author of Hana Yori Dango showed us thoughout the anime and manga that anyone who starts off being hard can also find their soft side because of love and that is shown though Tsukasa Domyouji.
A student at Tomobiki High School, Class 2-4, Ataru suffers from an incredible amount of bad luck, having been born on the unluckiest day of the Bhuddist calendar. He is very lecherous, stupid, and lazy. Though he often tries to escape from Lum and flirts with other women, he really does have feelings for her. Ataru's main goal in life is to live in the center of a harem composed of exotic and beautiful women (including Lum and most of her alien friends). His pick-up techniques would creep out most stalkers. Usually, he just walks up to a woman he's never met before and asks for her name, phone number, and address. Once he decides to go after a particular female, virtually no force on Earth (or from outer space) can stop him. He refused to admit it but, deep down, he proved in the later episodes that it was Lum that he truly loved. (source:Wikipedia)
Jariten, known to everyone as "Ten" is Lum's little cousin. Ten is a bratty and smart-mouthed alien toddler. Like all oni, Ten has powers of his own. He can fly and breathe fire. But he is an inexperienced child so his flying is awkward and slow, and his fire breathing isn't always effective. Ten is a child, but sure doesn't act his age. He has a certain level of adult intelligence which is quite shocking for someone still in diapers. One result of being precocious is that Ten only has eyes for older women. Yet Ten is still essentially a child and quite naive. Around women he is usually cute and diminutive. When he's near men he's his usual self. Loud, pesky and often aggressive. Ten came to earth to meet Lum's new husband but was disappointed at what he found. From the moment they've met, Ataru and Ten have been at each other's throats. Because Ataru is such an idiot, Ten doesn't think he deserves Lum. Therefore he decides to live with them to keep an eye on Ataru. (info from Furinkan.com)
His nickname is derived from his hairstyle ("kakugari (カクガリ)" means "crew cut"), he has a large build. He is the least used of the stormtroopers and he often seen with Chibi. He is also the one who beats up Chibi the most.
Honda appears as one of the more prominent characters to appear in the second half of the anime, unlike a majority of the characters that were not heavily involved in the backstory of the game. He is voiced by Daisuke G�ri in the Japanese version, and Richard Epcar in the english dub. His personality is relatively unchanged from that in the games, however his goal is shown to be to fight for cash compared to his in-game goal of proving the strength of sumo to the world. Several aspects of his character appearance here saw usage in the Street Fighter Alpha series much like many other characters, but moreso in the Capcom vs. SNK games, where outright nods (such as his run anim being a direct copy of his attempt to charge into Bison) were included in the game. He's first seen wrestling with Dhalsim in Calcutta to win prize money. Dhalsim manages to slip away from his grip however, and attempts to mentally subdue Honda. Ryu's presence however distracts Dhalsim enough for Honda to regain control of the match and win due to forfeit. Honda catches up with Ryu, recognizing he helped him win and the fact Ryu is a fellow Japanese fighter, giving him half the prize money as well as a place to stay for a while. Guile then Bison find Ryu eventually however. While Ryu tries to deal with a brainwashed Ken, Honda charges forward to take on Bison, only for Bison to teleport out of his path and Ken to send him stumbling forward, straight into Balrog. He and Balrog end up fighting, eventually with both of them falling off a nearby cliff. However Honda seems to recover quickly enough, seen lugging both the unconscious Balrog and Guile back just as Ryu and Ken defeat Bison. (Source: Wikipedia)
Sakura's wandering monk uncle. Cherry's real name is Sakuranbou, which literally means “cherry” in Japanese. But because the word's kanji can be read to mean "deranged monk," a phrase that is quite accurate in describing him, he prefers to be called by the English word. Cherry has amazing spiritual powers (or so he claims) and he often predicts doom for Ataru (no great feat). He has a habit of popping up out of nowhere, often from very strange places. His ugly face and very short stature are frequently used for comedic effect. Cherry has made a vow of asceticism, living in a tent in an empty lot not far from Ataru's house. However, this vow apparently doesn't apply to food, as he is an enormous mooch. Rei Hino of Sailor Moon's Grandpa looks a lot like Cherry. SOURCE: http://en.wikipedia.org/wiki/Sakuranbou#Sakuranbou