Maes Hughes's wife, and Elicia Hughes's mother, she is a kind and caring person. Gracia appears peripherally throughout the series and allows Winry to stay at her house when she is in Central and Sheska to frequently visit. In the manga, it is revealed that she and Hughes met before he was sent out to the battlefield during the Ishval War.
A pair of serial killers who had their souls sealed into a single suit of armor (one sealed in the head and one sealed in the suit) and became one of the guardians of the 5th laboratory under the joint alias of "Number 48," assigned to kill any intruders. In an omake (a short bonus comic), the older brother is a cat lover while the younger is a dog lover, which leads them to bicker at times. However, the younger brother always wins because he actually has body parts, while the older brother only has a head.
Mrs. Bradley is the wife of the Fuhrer, King Bradley. A kind and trusting wife. Though she rarely appears in either series, usually accompanying Selim, Mrs. Bradley's appearances usually fall under the category of comic relief as she speaks jovially of her familial life and romantic past with the Fuhrer.
Nina's father was Shou Tucker, the Sowing Life Alchemist. When her father became desperate in forming another talking chimera he transmuted her and her dog into a chimera that was able to speak the human language. Shortly after, she is killed by Scar to put her out of her misery. Later on in the first anime, with the philosopher's stone, the disfigured Chimeric Shou Tucker is able to resurrect his fallen daughter into the form of a chimera hommuncuelus, an artificial human being. However, she never speaks and little is known about what happens after that.
A frog-like chimera who was initially one of Kimblee's bodyguards, but deserted and joined Scar instead.
Originally one of Kimblee's bodyguards, Heinkel and Darius are blasted by Kimblee along with Ed, and ends up joining Ed when he saves them. Heinkel's chimera form is that of a humanoid lion.
Sloth is the fifth Homunculus created by Father. Appearing as a giant, muscular, but mentally slow man, Sloth spends most of the story digging the country spanning underground tunnels that make up the Father's mysterious transmutation circle. A conversation between Greed and Lust implies that Sloth have dug tunnels for at least a hundred years. Not surprisingly, he seems eager to finish his work so he can rest at last. In the first anime, Sloth was inadvertently created in the failed human transmutation of Ed and Al, and appeared as their mother, quite the opposite of what he is characterized as in Fullmetal Alchemist: Brotherhood. After completion of the tunnel, Sloth is ordered to Central on the Promised Day, where he is to kill anyone who could potentially ruin Father's plan, most notably General Armstrong. She manages to hold him off with the help of her younger brother, but the appearance of the Mannequin Soldiers and Central troops throw off their tactics. Sloth reveals his Homunculus trait, the ability to move at supersonic speeds, and nearly kills the two before Izumi and Sig Curtis arrive and help destroy Sloth's Philosopher's Stone.